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G6PD--an old bottle with new wine.

Chang Gung medical journal - 1 Sept 2005

Ho Hung-Yao, Cheng Mei-Ling, Chiu Daniel Tsun-Yee

Abstract excerpt

The major role of glucose-6-phosphate dehydrogenase (G6PD) is to generate reduced nicotinamide adenine dinucleotide phosphate (NADPH), which is indispensable to reductive metabolism and maintenance of cellular redox homeostasis. Most advances in this field have been made in the pathophysiology of G6PD-deficient erythrocytes and the molecular characterization of different G6PD variants. Recently, numerous studies...

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PMID: 16323551

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