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Glucose-6-Phosphate Dehydrogenase Deficiency: Disadvantages and Possible Benefits

1 Mar 2013

Abstract excerpt

We review here some recent data about Glucose-6-phosphate dehydrogenase (G6PD), the housekeeping X-linked gene encoding the first enzyme of the pentose phosphate pathway (PPP), a NADPH-producing dehydrogenase. This enzyme has been popular among clinicians, biochemists, geneticists and molecular biologists because it is the most common form of red blood cell enzymopathy. G6PD deficient erythrocytes do not generate...

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PMID: 23534950
DOI: 10.2174/1871529x11313010008

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