Article
5A/6A polymorphism of the stromelysin-1 gene and angiographic restenosis after coronary artery stenting.
Journal of the Chinese Medical Association : JCMA - 1 Nov 2005
Chiou Kuan-Rau, Chung Sheng-Liang, Charng Min-Ji
Abstract excerpt
BACKGROUND: Coronary stent deployment is a major advance in interventional treatment, but 20-40% of patients still develop in-stent restenosis (ISR) due to neointimal hyperplasia. Genetic factors play a role in restenosis. This study investigated the frequency of 5A/6A polymorphism in the promoter of the stromelysin-1 gene, and the issue of whether it contributes to restenosis among patients receiving coronary...
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