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Article

4G/5G polymorphism of the plasminogen activator inhibitor-1 gene and risk of restenosis after coronary artery stenting.

American heart journal - 1 Nov 2003

Böttiger Corinna, Koch Werner, Lahn Christina, Mehilli Julinda, von Beckerath Nicolas, Schömig Albert, Kastrati Adnan

Abstract excerpt

BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) has been proposed as a candidate risk factor for restenosis after coronary artery stenting. Transcription, level, and activity of PAI-1 are influenced by the 4G/5G polymorphism in the promoter region of PAI-1 gene. The polymorphism may therefore affect wound-healing processes in injured blood vessels and influence restenosis. METHODS: In 1850 consecutive...

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PMID: 14597935
DOI: 10.1016/S0002-8703(03)00363-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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