Article
Adaptation of methicillin-resistant Staphylococcus aureus in the face of vancomycin therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jan 2006
Sakoulas George, Moellering Robert C, Eliopoulos George M
Abstract excerpt
For the past 2 decades, vancomycin has served as the cornerstone of therapy against serious methicillin-resistant Staphylococcus aureus infections. This role is increasingly challenged by questions of efficacy, including reduced efficacy against infections caused by glycopeptide-intermediate S. aureus strains. In an evaluation of clinical glycopeptide-intermediate S. aureus isolates and serial, clinical...
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