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Article

Impact of sarA on antibiotic susceptibility of Staphylococcus aureus in a catheter-associated in vitro model of biofilm formation.

Antimicrobial agents and chemotherapy - 1 Jun 2009

Weiss Elizabeth C, Spencer Horace J, Daily Sonja J, Weiss Brian D, Smeltzer Mark S

Abstract excerpt

Mutation of the staphylococcal accessory regulator (sarA) in Staphylococcus aureus limits but does not abolish the capacity of the organism to form a biofilm. As a first step toward determining whether this limitation is therapeutically relevant, we carried out in vitro studies comparing the relative susceptibility of an S. aureus clinical isolate (UAMS-1) and its isogenic sarA mutant (UAMS-929) in the specific...

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Identifiers

PMID: 19289527
DOI: 10.1128/AAC.01432-08
PMCID: PMC2687244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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