Article
Accessory Gene Regulator Polymorphism and Vancomycin Minimum Inhibitory Concentration in Methicillin-Resistant Staphylococcus aureus.
Annals of laboratory medicine - 1 Jul 2015
Park Min-Jeong, Kim Han-Sung, Kim Hyun Soo, Kim Jae-Seok, Song Wonkeun, Kim Mi Young, Lee Young Kyung, Kang Hee Jung
Abstract excerpt
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with a vancomycin minimum inhibitory concentration (MIC) of 2 µg/mL presents a high rate of therapeutic failure in response to vancomycin. In addition, polymorphism in accessory gene regulator (agr) is associated with vancomycin therapeutic effects. The association between agr polymorphism and vancomycin MICs was investigated in MRSA...
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