Article
Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia.
Antimicrobial agents and chemotherapy - 1 Sept 2008
McCalla Carlo, Smyth Davida S, Robinson D Ashley, Steenbergen Judith, Luperchio Steven A, Moise Pamela A, Fowler Vance G, Sakoulas George
Abstract excerpt
In a recent landmark trial of bacteremia caused by methicillin-resistant Staphylococcus aureus (MRSA) isolates, vancomycin MICs were >or=1 microg/ml for only 16% of the isolates, and accessory gene regulator (agr) function as measured by delta-hemolysin activity was absent or reduced in only 28.1% of the isolates. This clinical study did not capture a population of MRSA isolates predictive of vancomycin treatment...
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