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Accessory Gene Regulator ( <i>agr</i> ) Locus in Geographically Diverse <i>Staphylococcus aureus</i> Isolates with Reduced Susceptibility to Vancomycin

1 May 2002

Abstract excerpt

The majority of infections with glycopeptide intermediate-level resistant Staphylococcus aureus (GISA) originate in biomedical devices, suggesting a possible increased ability of these strains to produce biofilm. Loss of function of the accessory gene regulator (agr) of S. aureus has been suggested to confer an enhanced ability to bind to polystyrene. We studied agr in GISA, hetero-GISA, and related...

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PMID: 11959587
DOI: 10.1128/aac.46.5.1492-1502.2002

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