Article
Quasispecies made simple.
PLoS computational biology - 1 Nov 2005
Bull J J, Meyers Lauren Ancel, Lachmann Michael
Abstract excerpt
Quasispecies are clouds of genotypes that appear in a population at mutation-selection balance. This concept has recently attracted the attention of virologists, because many RNA viruses appear to generate high levels of genetic variation that may enhance the evolution of drug resistance and immune escape. The literature on these important evolutionary processes is, however, quite challenging. Here we use simple...
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