Article
Quasispecies as a matter of fact: viruses and beyond.
Virus research - 1 Dec 2011
Ojosnegros Samuel, Perales Celia, Mas Antonio, Domingo Esteban
Abstract excerpt
We review the origins of the quasispecies concept and its relevance for RNA virus evolution, viral pathogenesis and antiviral treatment strategies. We emphasize a critical point of quasispecies that refers to genome collectivities as the unit of selection, and establish parallels between RNA viruses and some cellular systems such as bacteria and tumor cells. We refer also to tantalizing new observations that...
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