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Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana.

Genetics - 1 Apr 2006

Litvintseva Anastasia P, Thakur Rameshwari, Vilgalys Rytas, Mitchell Thomas G

Abstract excerpt

We applied multilocus sequence typing (MLST) to investigate the population structure and mode of reproduction of Cryptococcus neoformans var. grubii (serotype A). This MLST system utilizes 12 unlinked polymorphic loci, which are dispersed on nine different chromosomes, and allows the unambiguous identification of closely related strains of serotype A. We compared MLST analyses with the conventional genotyping...

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Identifiers

PMID: 16322524
DOI: 10.1534/genetics.105.046672
PMCID: PMC1456387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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