Article

Genomic epidemiology and ecology of Cryptococcus neoformans var. grubii in southern Africa

2016-01-01

Abstract excerpt

Despite the increased availability of antiretroviral therapy, cryptococcal meningitis remains a neglected disease that is responsible for up to 30% of AIDS related deaths. In the light of next generation sequencing technologies, this thesis investigates the molecular epidemiology of Cryptococcus neoformans var. grubii (Cng) in southern Africa. Sampling in the field and laboratory isolation yielded 37 environmental...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8b970092-28ee-5a09-b174-27097b1d7ad7
DOI: 10.25560/42540

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomic epidemiology and ecology of Cryptococcus neoformans var. grubii in southern AfricaDOI 10.25560/42540Read

Genomic epidemiology of Cryptococcus yeasts identifies adaptation to environmental niches underpinning infection across an African HIV/AIDS cohort.Semantic proximity Read

Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana.Semantic proximity Read

A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands.Semantic proximity Read

The evolution of Cryptococcus neoformans var. grubii in the context of clinical disease using multilocus sequence typingSemantic proximity Read

Global Molecular Epidemiology of<i>Cryptococcus neoformans</i>and<i>Cryptococcus gattii</i>: An Atlas of the Molecular TypesSemantic proximity Read

Advances in Cryptococcus genomics: insights into the evolution of pathogenesis.Semantic proximity Read

Evidence that the Human Pathogenic Fungus Cryptococcus neoformans var. grubii May Have Evolved in AfricaSemantic proximity Read

Cryptococcus neoformans and Cryptococcus gattii Species Complexes in Latin America: A Map of Molecular Types, Genotypic Diversity, and Antifungal Susceptibility as Reported by the Latin American Cryptococcal Study GroupSemantic proximity Read

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population LevelSemantic proximity Read

Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformansSemantic proximity Read

Population genomics of <i>Cryptococcus neoformans</i> var. <i>grubii</i> reveals new biogeographic relationships and finely maps hybridizationSemantic proximity Read

MLST reveals a clonal population structure for Cryptococcus neoformans molecular type VNI isolates from clinical sources in Amazonas, Northern-BrazilSemantic proximity Read