Article
Low diversity Cryptococcus neoformans variety grubii multilocus sequence types from Thailand are consistent with an ancestral African origin.
PLoS pathogens - 1 Apr 2011
Simwami Sitali P, Khayhan Kantarawee, Henk Daniel A, Aanensen David M, Boekhout Teun, Hagen Ferry, Brouwer Annemarie E, Harrison Thomas S, Donnelly Christl A, Fisher Matthew C
Abstract excerpt
The global burden of HIV-associated cryptococcal meningitis is estimated at nearly one million cases per year, causing up to a third of all AIDS-related deaths. Molecular epidemiology constitutes the main methodology for understanding the factors underpinning the emergence of this understudied, yet increasingly important, group of pathogenic fungi. Cryptococcus species are notable in the degree that virulence...
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