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Molecular typing of clinical Cryptococcus neoformans isolates collected in Germany from 2004 to 2010.

Medical microbiology and immunology - 1 Oct 2014

Sanchini Andrea, Smith Ilka McCormick, Sedlacek Ludwig, Schwarz Roman, Tintelnot Kathrin, Rickerts Volker

Abstract excerpt

Cryptococcosis is a fungal infection mostly caused by Cryptococcus neoformans. We identified agents of cryptococcosis diagnosed in Germany from 2004 to 2010. We used multi-locus sequence typing (MLST) to understand the molecular epidemiology of cryptococcosis. Sero- and mating types of individual patient isolates were determined by PCR. MLST was performed using the seven-locus scheme. Allele and nucleotide...

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PMID: 24838744
DOI: 10.1007/s00430-014-0341-6

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