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Article

Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa.

Eukaryotic cell - 1 Dec 2003

Litvintseva Anastasia P, Marra Robert E, Nielsen Kirsten, Heitman Joseph, Vilgalys Rytas, Mitchell Thomas G

Abstract excerpt

The most common cause of fungal meningitis in humans, Cryptococcus neoformans serotype A, is a basidiomycetous yeast with a bipolar mating system. However, the vast majority (>99.9%) of C. neoformans serotype A isolates possess only one of the two mating type alleles (MATalpha). Isolates with the other allele (MATa) were recently discovered and proven to mate in the laboratory. It has been a mystery whether and...

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Identifiers

PMID: 14665451
DOI: 10.1128/EC.2.6.1162-1168.2003
PMCID: PMC326657

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