Article
Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana.
Molecular ecology - 1 Jul 2015
Chen Yuan, Litvintseva Anastasia P, Frazzitta Aubrey E, Haverkamp Miriam R, Wang Liuyang, Fang Charles, Muthoga Charles, Mitchell Thomas G, Perfect John R
Abstract excerpt
Cryptococcus neoformans var. grubii (Cng) is the most common cause of fungal meningitis, and its prevalence is highest in sub-Saharan Africa. Patients become infected by inhaling airborne spores or desiccated yeast cells from the environment, where the fungus thrives in avian droppings, trees and soil. To investigate the prevalence and population structure of Cng in southern Africa, we analysed isolates from 77...
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