Article
Lack of association between variations in the melanocortin 5 receptor gene and bipolar disorder.
Psychiatric genetics - 1 Dec 2005
Lohoff Falk W, Berrettini Wade H
Abstract excerpt
OBJECTIVE: The melanocortin 5 receptor gene maps to the bipolar susceptibility locus on chromosome 18p11.2. Given the biological role of melanocortins and their influence on the hypothalamic-pituitary-adrenal axis, the melanocortin 5 receptor gene is a plausible candidate gene for bipolar disorder. We tested the hypothesis that the potential functional variation Phe209Leu confers susceptibility to bipolar...
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