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Article

Cross-regulation among disparate antibiotic biosynthetic pathways of Streptomyces coelicolor.

Molecular microbiology - 1 Dec 2005

Huang Jianqiang, Shi Jing, Molle Virginie, Sohlberg Björn, Weaver David, Bibb Maureen J, Karoonuthaisiri Nitsara, Lih Chih-Jian, Kao Camilla M, Buttner Mark J, Cohen Stanley N

Abstract excerpt

A complex programme of regulation governs gene expression during development of the morphologically and biochemically complex eubacterial genus Streptomyces. Earlier work has suggested a model in which 'higher level' pleiotropic regulators activate 'pathway-specific' regulators located within chromosomal gene clusters encoding biosynthesis of individual antibiotics. We used mutational analysis and adventitious...

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PMID: 16313616
DOI: 10.1111/j.1365-2958.2005.04879.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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