Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system.

Journal of bacteriology - 1 Feb 2002

Ryding N Jamie, Anderson Todd B, Champness Wendy C

Abstract excerpt

The Streptomyces coelicolor absA two-component system was initially identified through analysis of mutations in the sensor kinase absA1 that caused inhibition of all four antibiotics synthesized by this strain. Previous genetic analysis had suggested that the phosphorylated form of AbsA2 acted as a negative regulator of antibiotic biosynthesis in S. coelicolor (T. B. Anderson, P. Brian, and W. C. Champness, Mol....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Regulator
Share to Ionophores
Share to Open Reading Frames

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Peptide Synthases

Share to Peptides

Share to Physical Chromosome Mapping

Share to RNA, Bacterial

Share to Streptomyces

Source

Open in PubMed Open full text

Identifiers

PMID: 11790750
DOI: 10.1128/JB.184.3.794-805.2002
PMCID: PMC139508

Genes

CDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system.PMID 11790750Read ↗

Transcriptional regulation of Streptomyces coelicolor pathway-specific antibiotic regulators by the absA and absB loci.Semantic proximity Read ↗

Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system.Semantic proximity Read ↗

Novel two-component systems implied in antibiotic production in Streptomyces coelicolor.Semantic proximity Read ↗

Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation.Semantic proximity Read ↗

afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation.Semantic proximity Read ↗

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor.Semantic proximity Read ↗

Antibiotic Production and Antibiotic Resistance: The Two Sides of AbrB1/B2, a Two-Component System of Streptomyces coelicolorSemantic proximity Read ↗

Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor.Semantic proximity Read ↗

Identification of Streptomyces coelicolor genes involved in regulation of antibiotic synthesis.Semantic proximity Read ↗

Genetic suppression analysis of non-antibiotic-producing mutants of the Streptomyces coelicolor absA locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.