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Article

Transcriptional regulation of Streptomyces coelicolor pathway-specific antibiotic regulators by the absA and absB loci.

Journal of bacteriology - 1 Jun 1998

Aceti D J, Champness W C

Abstract excerpt

The four antibiotics produced by Streptomyces coelicolor are all affected by mutations in the absA and absB loci. The absA locus encodes a putative two-component signal transduction system, and the absB locus encodes a homolog of Escherichia coli RNase III. We assessed whether these loci control...

Topics

Anti-Bacterial Agents
Base Sequence
DNA Primers
Gene Expression Regulation, Bacterial
Genes, Bacterial
Genes, Regulator
Mutation
Phenotype
Polymerase Chain Reaction
RNA, Bacterial
RNA, Messenger
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Streptomyces

Transcription, Genetic

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Identifiers

PMID: 9620958
DOI: 10.1128/JB.180.12.3100-3106.1998
PMCID: PMC107809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9620958-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Transcriptional regulation of Streptomyces coelicolor pathway-specific antibiotic regulators by the absA and absB loci.PMID 9620958Read ↗

Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system.Semantic proximity Read ↗

Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system.Semantic proximity Read ↗

Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation.Semantic proximity Read ↗

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor.Semantic proximity Read ↗

Antibiotic Production and Antibiotic Resistance: The Two Sides of AbrB1/B2, a Two-Component System of Streptomyces coelicolorSemantic proximity Read ↗

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Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulation.Semantic proximity Read ↗

afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Identification of Streptomyces coelicolor genes involved in regulation of antibiotic synthesis.Semantic proximity Read ↗

Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Novel two-component systems implied in antibiotic production in Streptomyces coelicolor.Semantic proximity Read ↗

Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin.Semantic proximity Read ↗

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