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Article

Role of ICAM1 in invasion of human breast cancer cells

17 Mar 2005

Abstract excerpt

We identified previously a region on chromosome 19p13.2 spanning the genes encoding the intercellular adhesion molecules (ICAM), ICAM1, ICAM4 and ICAM5 as a breast cancer susceptibility locus. Genetic variants in this region were also associated with indicators of disease severity, including higher rates of metastases to other organs. Based on this association, we set out to explore the role of ICAM1 in...

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PMID: 15774488
DOI: 10.1093/carcin/bgi070

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