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Article

A truncated acidic domain in Xenopus TRF1.

Gene - 15 Mar 2006

Crumet N, Carlson R L, Drutman S B, Shampay J

Abstract excerpt

Telomere function is mediated by a complex of proteins bound to double-stranded and single-stranded telomeric repeats. A key player in this complex is TRF1, which binds to duplex TTAGGG repeats and acts as a negative regulator of telomere length. This protein's domain structure, as defined by studies with mammalian orthologs, consists of an N-terminal acidic domain, a dimerization domain, and a C-terminal Myb DNA...

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Identifiers

PMID: 16309855
DOI: 10.1016/j.gene.2005.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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