Article
Expression of wild-type and mutant p53 proteins by recombinant vaccinia viruses.
Nucleic acids research - 11 Jul 1992
Ronen D, Teitz Y, Goldfinger N, Rotter V
Abstract excerpt
To facilitate the purification of wild type p53 protein, we established a recombinant p53 vaccinia viral expression system. Using this efficient eukaryotic expression vector, we found that the expressed p53 proteins retained their specific structural characteristics. A comparison between wild type and mutant p53 proteins showed the conservation of the typical subcellular localization and the expression of...
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