Article
An essential GTPase promotes assembly of preribosomal RNA processing complexes.
Molecular cell - 23 Nov 2005
Karbstein Katrin, Jonas Stefanie, Doudna Jennifer A
Abstract excerpt
Ribosome biogenesis in eukaryotes is a highly regulated process involving hundreds of transiently associated proteins and RNAs. Although most of these assembly factors have been genetically linked to specific step(s) in the biogenesis pathway, their biochemical functions are generally unknown. Bms1, an essential protein in yeast, is the only known GTPase required for biosynthesis of the 40S ribosomal subunit and...
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