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Article

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps.

The EMBO journal - 15 Nov 2001

Saveanu C, Bienvenu D, Namane A, Gleizes P E, Gas N, Jacquier A, Fromont-Racine M

Abstract excerpt

Eukaryotic ribosome maturation depends on a set of well ordered processing steps. Here we describe the functional characterization of yeast Nog2p (Ynr053cp), a highly conserved nuclear protein. Nog2p contains a putative GTP-binding site, which is essential in vivo. Kinetic and steady-state measurements of the levels of pre-rRNAs in Nog2p-depleted cells showed a defect in 5.8S and 25S maturation and a concomitant...

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Identifiers

PMID: 11707418
DOI: 10.1093/emboj/20.22.6475
PMCID: PMC125736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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