Article

Exploration of the proxiOME of large subunit ribosomal proteins reveals Acl1 and Bcl1 as cooperating dedicated chaperones of Rpl1

2025-09-18

Abstract excerpt

<h4>ABSTRACT</h4> The eukaryotic ribosome consists of four ribosomal RNAs (rRNAs) and around 80 ribosomal proteins (r-proteins). Most r-proteins, due to their extensive interactions with rRNA, contain highly basic regions, which can predispose them to aggregation prior to their assembly. Accordingly, dedicated chaperones (DCs) and importins have been shown to play a crucial role in safeguarding newly synthesized...

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Literature Corpus work: aec578a7-68e3-5f25-ba33-185d3b924cbf
DOI: 10.1101/2025.09.18.677003

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