Article
Sequential protein association with nascent 60S ribosomal particles.
Molecular and cellular biology - 1 Jul 2003
Saveanu Cosmin, Namane Abdelkader, Gleizes Pierre-Emmanuel, Lebreton Alice, Rousselle Jean-Claude, Noaillac-Depeyre Jacqueline, Gas Nicole, Jacquier Alain, Fromont-Racine Micheline
Abstract excerpt
Ribosome biogenesis in eukaryotes depends on the coordinated action of ribosomal and nonribosomal proteins that guide the assembly of preribosomal particles. These intermediate particles follow a maturation pathway in which important changes in their protein composition occur. The mechanisms involved in the coordinated assembly of the ribosomal particles are poorly understood. We show here that the association of...
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