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Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Clinical Molecular and Genetic Studies on Alzheimer’s Disease

1 Jan 2012

Abstract excerpt

Recent advances in clinical molecular and genetic studies on Alzheimer's disease (AD) are summarized here. Cerebrospinal fluid (CSF) Aβ42 and tau are the most sensitive biomarkers for the diagnosis of AD and prediction of its onset following mild cognitive impairment (MCI). Based on this progress, new diagnostic criteria for AD dementia, MCI due to AD, and preclinical AD were proposed by the National Institute of...

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PMID: 22382661
DOI: 10.1254/jphs.11r13fm

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