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Article

A modified, dual reporter TOXCAT system for monitoring homodimerization of transmembrane segments of proteins.

Biochemical and biophysical research communications - 6 Jan 2006

Lis Maciej, Blumenthal Kenneth

Abstract excerpt

The TOXCAT assay system developed by Russ and Engelman [TOXCAT: a measure of transmembrane helix association in a biological membrane, Proc. Natl. Acad. Sci. USA 96 (1999) 863-868] provides an in vivo means of selecting for and evaluating the strength of interaction between identical transmembrane alpha-helices. In the course of utilizing TOXCAT to study the architecture of a sodium channel hNa(V)1.5, an...

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Identifiers

PMID: 16297866
DOI: 10.1016/j.bbrc.2005.11.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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