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Article

A ToxR-based dominant-negative system to investigate heterotypic transmembrane domain interactions.

Proteins - 1 Dec 2006

Lindner Eric, Langosch Dieter

Abstract excerpt

The ToxR transcription activator system is a genetic tool widely used to examine homotypic interactions of alpha-helical transmembrane domains that drive or support oligomerization of integral membrane proteins. Here, we present a variant of this system that was developed to investigate heterotypic interactions. In this system, a homotypically interacting transmembrane domain within the ToxR protein is...

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PMID: 17066379
DOI: 10.1002/prot.21226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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