Article
Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris.
The Journal of investigative dermatology - 1 Nov 2005
Hüffmeier Ulrike, Lascorz Jesús, Traupe Heiko, Böhm Beate, Schürmeier-Horst Funda, Ständer Markward, Kelsch Reinhard, Baumann Claudia, Küster Wolfgang, Burkhardt Harald, Reis André
Abstract excerpt
The gene for solute carrier family 12 member A8 has recently been proposed as a candidate gene for psoriasis susceptibility (PSORS5) on chromosome 3q based on association of five single nucleotide polymorphisms (SNP) in Swedish patients. To investigate whether this locus is relevant for German psoriasis vulgaris (PsV) patients, we analyzed a group of 210 trios and a case-control group including 375 patients....
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