Article
Lack of association of glutathione S-transferase P1 Ile105Val polymorphism with aspirin-intolerant asthma.
The Korean journal of internal medicine - 1 Sept 2005
Oh Jung-Mi, Kim Seung-Hyun, Suh Chang-Hee, Nahm Dong-Ho, Park Hae-Sim, Lee Young-Mok, Lee June-Hyuk, Park Choon-Sik, Shin Hyung-Doo
Abstract excerpt
BACKGROUND: Glutathion S-transferase P1 (GSTP1), the abundant isoform of glutathione S-transferase in lung epithelium, plays an important role in cellular protection against oxidative stress and toxic foreign chemicals. GSTP1 (Ile105Val) polymorphism has been reported to be associated with asthma related phenotypes such as atopy and bronchial hyperresponsiveness. Therefore we investigated whether this...
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