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Article

Association study of Glutathione S-transferase P1 (GSTP1) with asthma and bronchial hyper-responsiveness in two German pediatric populations.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Sept 2005

Nickel Renate, Haider Assja, Sengler Claudia, Lau Susanne, Niggemann Bodo, Deichmann Klaus A, Wahn Ulrich, Heinzmann Andrea

Abstract excerpt

Glutathione S-Transferase P1 (GSTP1) is an important enzyme in the detoxification of products of oxidative stress. Several studies have shown an association of the amino acid variant Ile105Val with bronchial asthma and the reaction of the lung to inhalant pollutants. The aim of this study was to test the two known amino acid variants in GSTP1 for association with bronchial asthma and airway hyper-responsiveness...

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Source

Identifiers

PMID: 16176403
DOI: 10.1111/j.1399-3038.2005.00307.x

Genes

GSTP1

Provenance

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Association study of Glutathione S-transferase P1 (GSTP1) with asthma and bronchial hyper-responsiveness in two German pediatric populations.PMID 16176403Read ↗

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