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Article

Estimating the additive genetic effect of the X chromosome.

Genetic epidemiology - 1 Dec 2005

Kent Jack W, Dyer Thomas D, Blangero John

Abstract excerpt

We propose a method for efficient estimation of the additive genetic effect of the X chromosome with explicit modeling of eutherian-type dosage compensation. The theoretical derivation of the variance-components model for X-linked loci is reviewed in detail. We develop a model of dosage compensation that allows for both incomplete and heterogeneous lyonization, the existence of which is suggested by recent...

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Identifiers

PMID: 16294301
DOI: 10.1002/gepi.20093
PMCID: PMC3617965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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