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Article

Poly(A) tail recognition by a viral RNA element through assembly of a triple helix.

Science (New York, N.Y.) - 26 Nov 2010

Mitton-Fry Rachel M, DeGregorio Suzanne J, Wang Jimin, Steitz Thomas A, Steitz Joan A

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus produces a highly abundant, nuclear noncoding RNA, polyadenylated nuclear (PAN) RNA, which contains an element that prevents its decay. The 79-nucleotide expression and nuclear retention element (ENE) was proposed to adopt a secondary structure like that of a box H/ACA small nucleolar RNA (snoRNA), with a U-rich internal loop that hybridizes to and protects the PAN RNA...

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Identifiers

PMID: 21109672
DOI: 10.1126/science.1195858
PMCID: PMC3074936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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