Article
Alternative Polyadenylation of Human Bocavirus at Its 3' End Is Regulated by Multiple Elements and Affects Capsid Expression.
Journal of virology - 1 Feb 2017
Hao Sujuan, Zhang Junmei, Chen Zhen, Xu Huanzhou, Wang Hanzhong, Guan Wuxiang
Abstract excerpt
Alternative processing of human bocavirus (HBoV) P5 promoter-transcribed RNA is critical for generating the structural and nonstructural protein-encoding mRNA transcripts. The regulatory mechanism by which HBoV RNA transcripts are polyadenylated at proximal [(pA)p] or distal [(pA)d] polyadenylation sites is still unclear. We constructed a recombinant HBoV infectious clone to study the alternative polyadenylation...
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