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Article

An extended stem-loop 1 is necessary for human immunodeficiency virus type 2 replication and affects genomic RNA encapsidation.

Journal of virology - 1 Apr 2007

Lanchy Jean-Marc, Lodmell J Stephen

Abstract excerpt

Genomic RNA encapsidation in lentiviruses is a highly selective and regulated process. The unspliced RNA molecules are selected for encapsidation from a pool of many different viral and cellular RNA species. Moreover, two molecules are encapsidated per viral particle, where they are found associated as a dimer. In this study, we demonstrate that a 10-nucleotide palindromic sequence (pal) located at the 3' end of...

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Identifiers

PMID: 17229705
DOI: 10.1128/JVI.02025-06
PMCID: PMC1866085

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