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Article

In vivo expression of a conditional TGF-beta1 transgene: no evidence for TGF-beta1 transgene expression in SM22alpha-tTA transgenic mice.

Journal of molecular and cellular cardiology - 1 Jan 2006

Lee Sunyoung, Agah Ramtin, Xiao Ming, Frutkin Andrew D, Kremen Michal, Shi Haikun, Dichek David A

Abstract excerpt

Transforming growth beta-1 (TGF-beta1) appears to play a critical role in the regulation of arterial intimal growth and the development of atherosclerosis. TGF-beta1 is expressed at increased levels in diseased arteries; however, its role in disease development remains controversial. Experiments in which TGF-beta1 is overexpressed in the artery wall of transgenic mice could clarify the role of TGF-beta1 in the...

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Identifiers

PMID: 16288910
DOI: 10.1016/j.yjmcc.2005.09.015
PMCID: PMC1444940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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