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Article

'Stop-codon-specific' restriction endonucleases: their use in mapping and gene manipulation.

Gene - 1 Jul 1992

Rowland G C, Lim P P, Glass R E

Abstract excerpt

Certain restriction endonucleases recognise target sequences that contain the stop triplet TAG and are commonly either 4 or 6 bp in length. Interestingly, these restriction targets do not occur at the frequency expected on the basis of base composition and size. For example, the tetranucleotide MaeI recognition sequence (CTAG) occurs considerably less commonly (5-8-fold) in the genome of Escherichia coli (and...

Topics

Bacteria
Base Composition
Codon
DNA, Bacterial
Deoxyribonucleases, Type II Site-Specific
Endodeoxyribonucleases
Escherichia coli
Genetic Markers
Genome, Bacterial
Mutation
Protein Engineering

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Transfer

Restriction Mapping

Source

Identifiers

PMID: 1628840
DOI: 10.1016/0378-1119(92)90624-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1628840-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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