Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes.

doi:10.1073/pnas.0508989102

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Article

Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes.

Proceedings of the National Academy of Sciences of the United States of America - 29 Nov 2005

Grishok Alla, Sharp Phillip A

Abstract excerpt

Short RNA regulatory molecules, microRNAs, and short interfering RNAs participate in a range of developmental gene networks by base-pairing with their target sequences. Consistent with these findings, genes required for the biogenesis and function of short interfering RNAs and microRNAs, dicer (dcr-1 in Caenorhabditis elegans) and argonaute homologs, are essential for development in diverse organisms, including...

Topics

Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Nucleus Division
Chromatin Immunoprecipitation
Cyclin E
Gene Expression Regulation
Green Fluorescent Proteins
Indoles
Intestines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

RNA Interference

RNA, Small Interfering

Repressor Proteins

Reverse Transcriptase Polymerase Chain Reaction

Ribonuclease III

Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 16287966
DOI: 10.1073/pnas.0508989102
PMCID: PMC1297700

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