Article
The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans.
Molecular and cellular biology - 1 Dec 2005
Román Elvira, Nombela César, Pla Jesús
Abstract excerpt
The Sho1 adaptor protein is an important element of one of the two upstream branches of the high-osmolarity glycerol (HOG) mitogen-activated protein (MAP) kinase pathway in Saccharomyces cerevisiae, a signal transduction cascade involved in adaptation to stress. In the present work, we describe its role in the pathogenic yeast Candida albicans by the construction of mutants altered in this gene. We report here...
Topics
- Candida albicans
- Cell Wall
- Fungal Proteins
- Genetic Complementation Test
- Histidine Kinase
- Membrane Proteins
- Mitogen-Activated Protein Kinase Kinases
- Morphogenesis
- Mutation
- Osmotic Pressure
- Oxidative Stress
- Protein Kinases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins