Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans

4 Dec 2018

Abstract excerpt

The high-osmolarity glycerol response (HOG) pathway is pivotal in environmental-stress response, differentiation, and virulence of Cryptococcus neoformans, which causes fatal meningoencephalitis. A putative membrane sensor protein, Sho1, has been postulated to regulate HOG pathway, but its regulatory mechanism remains elusive. In this study we characterized the function of Sho1 with relation to the HOG pathway in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal Infections and Studies
Share to Plant Disease Resistance and Genetics
Share to Plant-Microbe Interactions and Immunity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30564211
DOI: 10.3389/fmicb.2018.02958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformansPMID 30564211Read ↗

A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans.Semantic proximity Read ↗

Ssk2 mitogen-activated protein kinase kinase kinase governs divergent patterns of the stress-activated Hog1 signaling pathway in Cryptococcus neoformans.Semantic proximity Read ↗

Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway.Semantic proximity Read ↗

Specialization of the HOG Pathway and Its Impact on Differentiation and Virulence of<i>Cryptococcus neoformans</i>Semantic proximity Read ↗

The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans.Semantic proximity Read ↗

Stress Signaling Pathways for the Pathogenicity of CryptococcusSemantic proximity Read ↗

Remodeling of Global Transcription Patterns of <i>Cryptococcus neoformans</i> Genes Mediated by the Stress-Activated HOG Signaling PathwaysSemantic proximity Read ↗

Unraveling the cryptic functions of mitogen-activated protein kinases Cpk2 and Mpk2 in Cryptococcus neoformansSemantic proximity Read ↗

Sulphiredoxin plays peroxiredoxin‐dependent and ‐independent roles via the HOG signalling pathway in C ryptococcus neoformans and contributes to fungal virulenceSemantic proximity Read ↗

Hog1/p38 regulates the integrated stress response (ISR) and global transcriptomic changes in <i>C. neoformans</i> during oxidative stressSemantic proximity Read ↗

Multiple Roles of Ypd1 Phosphotransfer Protein in Viability, Stress Response, and Virulence Factor Regulation in Cryptococcus neoformansSemantic proximity Read ↗

Evolutionary unique <i>N</i> -glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.