Article
Simultaneous imaging of membrane antigen and the corresponding chromosomal locus in pathology archives.
Pathology international - 1 Dec 2005
Igarashi Hisaki, Yamashita Kimihiro, Suzuki Masaya, Kitayama Yasuhiko, Isogaki Jun, Maruyama Keiji, Sunayama Ken-Ichi, Tsuda Hitoshi, Ozawa Takachika, Kiyose Shinichiro, Sugimura Haruhiko
Abstract excerpt
A new procedure for the simultaneous staining of membranous antigens, such as tyrosine kinase-type cell surface receptor HER2 (c-erbB2), and the corresponding chromosome (chromosome 17 for c-erbB2) in the same cell for use in examining pathology archives is presented. A multistep procedure involving microwave-assisted fluorescence in situ hybridization and immunofluorescence yielded cell images having c-erbB2 on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
