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A method of identifying the blood contributor in mixture stains through detecting blood-specific mRNA polymorphism.

Electrophoresis - 1 Aug 2020

Liu Zidong, Gao Zhe, Wang Jiaqi, Shi Jie, Liu Jinding, Chen Deqing, Li Wenyan, Guo Jiangling, Cheng Xiaojuan, Hao Ting, Li Zeqin, Li Yanhua, Yan Jiangwei, Zhang Gengqian

Abstract excerpt

In the past decades, messenger RNA (mRNA) biomarkers have been employed to identify the origin of body fluids in forensic medicine. We hypothesized that the polymorphism of mRNA could be applied to identify individuals in mixture samples composed of two body fluids. In this study, we selected five blood-specific mRNA biomarkers of venous blood (SPTB, CD3G, AMICA1, ANK1, and GYPA) that encompass 16 SNPs to...

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PMID: 32388864
DOI: 10.1002/elps.202000053

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