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Article

Association between the TP63 and CIR1 polymorphisms and non-small cell lung cancer in Chinese population.

Journal of cardiothoracic surgery - 21 Jun 2026

Shen Yingying, Zheng Peiqing, Zheng Jiaxu, Gu Jianzhong

Abstract excerpt

OBJECTIVES: Lung cancer is a leading cause of cancer-related death globally, with non-small cell lung cancer (NSCLC) being the predominant form. Genetic factors significantly influence individual susceptibility. This study investigated the association of TP63 (rs7631358) and CIR1 (rs13009079) polymorphisms with NSCLC risk in a Chinese population. METHODS: A case-control study was conducted with 500 NSCLC patients...

Read the complete abstract on PubMed

Topics

Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Humans

Male

Middle Aged

Asian People

Carcinoma, Non-Small-Cell Lung

Case-Control Studies

China

Genetic Predisposition to Disease

Genotype

Lung Neoplasms

Polymorphism, Single Nucleotide

Transcription Factors

Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 42324549
DOI: 10.1186/s13019-026-04478-y
PMCID: PMC13531806

Genes

TP63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 26 Oct 2026.

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