Article
Differentiation of rhabdomyosarcoma cell lines using retinoic acid.
Pediatric blood & cancer - 1 Nov 2006
Barlow Jason W, Wiley Joe C, Mous Marieke, Narendran Aru, Gee Matthew F W, Goldberg Michael, Sexsmith Elizabeth, Malkin David
Abstract excerpt
BACKGROUND: Rhabdomyosarcoma (RMS) is the most frequent sporadic soft tissue sarcoma of childhood and adolescence. The overall 5-year survival rate for patients with RMS is 70% with the use of surgery, radiation, and chemotherapy. Novel therapeutic approaches are necessary to improve on these outcomes particularly among the more aggressive alveolar RMS (ARMS) and late stages of disease, where 5-year survival is...
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