Article
Streptococcal Protein FOG, a Novel Matrix Adhesin Interacting with Collagen I in Vivo
9 Nov 2005
Abstract excerpt
Group G streptococcus (GGS) is a human pathogen of emerging clinical significance. It causes skin and soft tissue infections, occasionally resulting in life-threatening conditions such as sepsis and necrotizing fasciitis. We recently identified FOG, a novel surface protein of GGS with fibrinogen binding and immune evasion properties. Here we investigated the role of FOG in streptococcal primary adhesion to host...
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