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Article

Streptococcus pyogenes recruits collagen via surface‐bound fibronectin: a novel colonization and immune evasion mechanism

15 Jan 2003

Abstract excerpt

This study aimed to characterize matrix assembly mechanisms on the surface of the human pathogen Streptococcus pyogenes. Among 125 S. pyogenes isolates, 61% were able to recruit collagen type IV via surface-bound fibronectin. Streptococcus gordonii expressing the fibronectin-binding repeat domain of S. pyogenes SfbI protein was equally potent in recruiting collagen, indicating that this domain was sufficient to...

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PMID: 12535082
DOI: 10.1046/j.1365-2958.2003.03352.x

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