Article
The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction.
The Journal of biological chemistry - 27 Jan 2006
McFadden Diane C, De Jesus Magdia, Casadevall Arturo
Abstract excerpt
The most distinctive feature of the human pathogenic fungus is a polysaccharide capsule that is essential for virulence and is composed primarily of glucuronoxylomannan (GXM) and galactoxylomannan (GalXM). GXM mediates multiple deleterious effects on host immune function, yet relatively little is known about its physical properties. The average mass of Cryptococcus neoformans GXM from four antigenically different...
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